Antigen-Specific T Cell Recall Assay To Screen Drugs For Off-Target Effects
E. Kleiman, G. Sierra, D. Magcase, M. V. George, P. M. Daftarian
The paper develops an in vitro recall assay to screen drugs for off-target effects on memory T cell expansion and function, showing differing impacts of GS-5734 and GS-445124.
bioRxiv · Aug 10, 2020 · PreprintImmunology