Machine learning prediction and phyloanatomic modeling of viral neuroadaptive signatures in the macaque model of HIV-mediated neuropathology
A. Ramirez-Mata, B. Rife Magalis, S. Marini, M. Salemi, D. Ostrov
The paper applies a machine learning approach to predict SIV-mediated encephalitis using gp120 sequences from macaques, identifying signatures associated with neuroadaptation and revealing their presence in non-CNS tissues.
bioRxiv · Jun 17, 2022Evolutionary Biology