Targeting endometrial cancer stem cell activity with metformin is inhibited by patient-derived adipocyte-secreted factors
S. J. Kitson, M. Rosser, D. P. Fischer, K. M. Marshall, R. B. Clarke, E. J. Crosbie
This paper shows metformin reduces endometrial cancer stem cell activity, but this effect is blocked by adipocyte-secreted factors from obese patients.
bioRxiv · Feb 28, 2019Cancer Biology