My host's enemy is my enemy: plasmids carrying CRISPR-Cas as a defence against phages
B. Siedentop, D. Ruegg, S. Bonhoeffer, H. Chabas
The paper develops a stochastic model to evaluate CRISPR-Cas plasmid-based anti-phage protection, showing it is robust except under specific parameter conditions where segregation loss enables phage outbreaks.
bioRxiv · Nov 1, 2023Microbiology