BioengineeringbioRxiv
Immune Cells and Inflammatory mediators cause endothelial dysfunction in a vascular microphysiological system
A. Rengarajan, H. E. Goldblatt, D. J. Beebe…·D. S. Boeldt
This study uses a vascular microphysiological system to show that inflammatory mediators and activated PBMCs disrupt endothelial function by increasing permeability and reducing Ca2+ signaling.
DOI 10.1039/d3lc00824j