Human Th17- and IgG3-associated autoimmunity induced by a translocating gut pathobiont
K. Gronke, M. Nguyen, N. Santamaria de Souza, J. Schumacher, Y. Yang, N. D. Sonnert, S. Leopold, A. Martin, R. Hallet, K. Richter, D. Schubert, G. M. Daniel, D. Dylus, M. Forkel, S. Manfredo Vieira, , M. A. Kriegel
This study shows that the gut pathobiont Enterococcus gallinarum induces human Th17 and IgG3 autoantibody responses linked to disease activity in autoimmune patients.
bioRxiv · Jun 29, 2023 · PreprintImmunology