Author

C. Schramm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Franke· 1 shared A. Martin· 1 shared A. Obraztsova· 1 shared A. Rovelet-Lecrux· 1 shared A. Shepherd· 1 shared A. Viswanathan· 1 shared B. J. Olson· 1 shared B. Ngo· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

A. Franke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human Th17- and IgG3-associated autoimmunity induced by a translocating gut pathobiont

K. Gronke, M. Nguyen, N. Santamaria de Souza, J. Schumacher, Y. Yang, N. D. Sonnert, S. Leopold, A. Martin, R. Hallet, K. Richter, D. Schubert, G. M. Daniel, D. Dylus, M. Forkel, S. Manfredo Vieira, , M. A. Kriegel

This study shows that the gut pathobiont Enterococcus gallinarum induces human Th17 and IgG3 autoantibody responses linked to disease activity in autoimmune patients.

bioRxiv · Jun 29, 2023 · PreprintImmunology

Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in PSC.

M. Awoniyi, J. Wang, B. Ngo, V. Meadows, J. Tam, A. Viswanathan, Y. Lai, S. Montgomery, M. Farmer, M. Kummen, L. B. Thingholm, C. Schramm, C. Bang, A. Franke, B. Schnabl, , R. B. Sartor

This study identifies protective and aggressive bacterial subsets and metabolites in PSC patients and mice, showing their impact on hepatobiliary inflammation and fibrosis.

bioRxiv · Oct 31, 2021 · PreprintMicrobiology

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

A. Rovelet-Lecrux, S. Feuillette, L. Miguel, C. Schramm, S. Pernet, I. Segalas-Milazzo, L. Guilhaudis, S. Rousseau, G. Riou, T. Frebourg, D. Campion, G. Nicolas, M. Lecourtois

This paper identifies SORL1 missense variants that impair SorLA maturation and trafficking, leading to increased Aβ secretion and linking these variants to Alzheimer's disease pathophysiology.

bioRxiv · Jun 18, 2021Cell Biology

sumrep: a summary statistic framework for immune receptor repertoire comparison and model validation

B. J. Olson, P. Moghimi, C. Schramm, A. Obraztsova, D. Ralph, J. A. Vander Heiden, M. Shugay, A. Shepherd, W. Lees, F. A. Matsen

sumrep is an R package for analyzing and comparing immune receptor repertoires, showing that recombination features are more discriminative than amino acid composition summaries and that generative models capture some but not all repertoire properties.

bioRxiv · Aug 6, 2019Immunology