Inhibition of a critical malaria host-pathogen interaction by a computationally designed inhibitor targeting Plasmodium vivax DBP
A. R. Tobin, R. Crow, D. V. Urusova, J. C. Klima, N. H. Tolia, E.-M. M. Strauch
The paper designs a small, stable protein inhibitor that blocks the Plasmodium vivax DBP-DARC interaction, offering a potential therapeutic for malaria.
bioRxiv · Feb 5, 2022 · PreprintBioengineering