Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis
V. Secli, E. Michetti, F. Pacello, F. Iacovelli, M. Falconi, M. L. Astolfi, D. Visaggio, P. Visca, S. Ammendola, A. Battistoni
This study identifies pyochelin's role in zinc homeostasis by showing it mediates cobalt import, which reduces zinc demand and supports Pseudomonas aeruginosa growth under zinc deficiency.
bioRxiv · Jan 7, 2024Microbiology