Evolutionary rates in human amyloid proteins reveal their intrinsic metastability
D. Zea, J. Mac Donagh, G. Benitez, C. E. G. Donadio, J. Marchetti, N. Palopoli, M. S. Fornasari, G. Parisi
The paper examines evolutionary rates of human amyloid proteins and finds they evolve faster than most human proteins but similar to secreted proteins, suggesting metastability influences their evolution.
bioRxiv · Sep 7, 2022 · PreprintEvolutionary Biology