pH-dependent allosteric remodeling of a bacterial riboswitch couples alkaline activation to metal sensing
Danea Palmer, Adrien Chauvier, Tomás F. D. Silva, Avery Ontiveros, Giovanni Bussi, Nils G. Walter, Tatiana V. Mishanina
This study shows how pH modulates Mn2+ sensing in the alx riboswitch through conformational changes and allosteric interactions.
Nucleic Acids Research · Sep 5, 2026Peer-reviewedBiochemistry