Sphingolipid regulation by yeast Mdm1 supports adaptive remodeling of the methionine transporter Mup1
Daniel Adebayo, Eseiwi Obaseki, Kashvi Vasudeva, Marwa Aboumourad, Scott Miller, Anne G. Ostermeyer‐Fay, Daniel Canals, Xun Bao, Jing Li, Hanaa H. Hariri
This study shows that yeast Mdm1 links sphingolipid homeostasis to Mup1 endocytic remodeling, improving amino acid homeostasis and lifespan under nutrient limitation.
Molecular Biology of the Cell · May 27, 2026Peer-reviewedCell Biology