Development and design rules for a modular human peptide-tag adaptor CAR T cell system
Alexander Haide Joechner, Melanie Mach, Michael Yeh, Riya Mehta, Taliah Khoury, Ecem Kurangil, Jinting Yan, Daniel Barton, Ziduo Li
This study develops a modular CAR T cell system, BRiDGE CAR, and identifies design rules for its activity based on CAR and adaptor configurations.
bioRxiv · Oct 23, 2026 · PreprintCancer Biology