Products of the Parkinson’s-disease related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival
Yusuke Toyoda, Cihan Erkut, Francisco Pan-Montojo, Sebastian Boland, Martin P. Stewart, Daniel J. M?ller, Wolfgang Wurst, Anthony A. Hyman, Teymuras V. Kurzchalia
The paper shows that D-lactate and glycolate, products of the Parkinson's-related protein DJ-1, support mitochondrial membrane potential and neuronal survival under stress.
bioRxiv · Jul 4, 2014Cell Biology