Pharmacology & ToxicologybioRxiv
Compound biological signatures facilitate phenotypic screening and target elucidation
Alvaro Cortes Cabrera, Daniel Lucena-Agell, Mariano Redondo-Horcajo…·Paula Petrone
The paper introduces BIOSEA, a method to identify compounds that reproduce desired cellular phenotypes using historical bioactivity data, finding novel inhibitors and drug repurposing opportunities.
DOI 10.1021/acschembio.6b00358