Author

Daniel Marten

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:Bayesian inference· 1 Research Focus:database / resource· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anne O’Donnell‐LuriaiD· 2 shared Benjamin M. NealeiD· 2 shared Daniel GoldsteiniD· 2 shared Greg Rohlicek· 2 shared Heidi L. RehmiD· 2 shared Jacqueline I. GoldsteiniD· 2 shared Jérémy GueziD· 2 shared Julia K. GoodrichiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Anne O’Donnell‐LuriaORCID

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3 papers

Recent·Most cited

Analysis of spliceosome-related coding and noncoding genes and pseudogenes reveals novel candidates

Olfa Messaoud, Stephanie P. DiTroia, Rahaf Tarawneh, Daniel Marten, Emily O’Heir, Melanie O’Leary, Lynn S. Pais, Vijay Ganesh, Moriel Singer‐Berk, Monica Wojcik, Kaitlin E. Samocha, Heidi L. Rehm, Christina Anne Austin-Tse, Anne O’Donnell‐Luria

The paper identifies novel spliceosome-related genes and pseudogenes associated with rare diseases using variant analysis and prioritization methods.

medRxiv · Aug 10, 2026 · PreprintGenetic & Genomic Medicine

Systematic common and rare variant association testing in 392,030 whole genomes in All of Us

Wenhan Lu, Robert J. Carroll, Matthew Solomonson, Jérémy Guez, Megan K. He, Daniel Marten, Alejandro Martínez-Carrasco, Ying Wang, Connor S. Dowd, Masahiro Kanai, Bram L. Gorissen, Aymone Kouame, James Brogan, Bennett J. Waxse, Ryan Samarakoon, , Konrad J. Karczewski

The paper performs large-scale GWAS and RVAS on 392,030 whole genomes from All of Us, identifying 49,863 associations and 193 novel pLoF gene-phenotype links through meta-analysis with UK Biobank.

medRxiv · May 12, 2026 · PreprintGenetic & Genomic Medicine

Integrating 730,947 exome sequences with clinical literature improves gene discovery

Jérémy Guez, Julia K. Goodrich, Mikhail A. Moldovan, Katherine R. Chao, Prathitha Kar, Ruchit Panchal, Michael W. Wilson, Kristen M. Laricchia, Greg Rohlicek, Dmitry Biba, Daniel Marten, Qin He, Philip W. Darnowsky, Riley H. Grant, Ben Weisburd, , Konrad J. Karczewski

gnomAD v4 (730,947 exomes) brings LOFTEE-2 loss-of-function annotation (0.90 precision, strict mode), missense-aware constraint, and LLM-mined literature evidence combined with constraint to rank disease genes.

medRxiv · Mar 25, 2026 · PreprintGenetic & Genomic Medicine✦ In-depth digest