Author

Daniel Schwartz

Oregon Health & Science University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Adam R. FergusoniD· 1 shared Alexander J. EhrenbergiD· 1 shared Anastasios V. TzingounisiD· 1 shared Bradley C Oh· 1 shared Bruce L. MilleriD· 1 shared Danielle CaeferiD· 1 shared Earnest Wang· 1 shared Fanny M. ElahiiD· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperNeuroscience

Adam R. FergusonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enlarged Perivascular Spaces are Associated with White Matter Injury, Brain Atrophy, Cognitive Decline and Markers of Inflammation in an Autosomal Dominant Vascular Neurodegenerative Disease (CADASIL)

Nikolaos Karvelas, Bradley C Oh, Earnest Wang, Yann Cobigo, Torie Tsuei, Stephen Fitzsimons, Alexander J. Ehrenberg, Michael D. Geschwind, Daniel Schwartz, Joel H. Kramer, Adam R. Ferguson, Bruce L. Miller, Lisa C. Silbert, Howard J. Rosen, Fanny M. Elahi

This study investigates the association between enlarged perivascular spaces (ePVS) and white matter injury, brain atrophy, cognitive decline, and inflammation markers in CADASIL, finding ePVS correlates with these pathologies and specific plasma proteins.

bioRxiv · Aug 17, 2023 · PreprintNeuroscience

The Okur-Chung Neurodevelopmental Syndrome (OCNDS) mutation CK2K198R leads to a rewiring of kinase specificity

Danielle Caefer, Nhat Q. Phan, Jennifer C. Liddle, Jeremy Lynn Balsbaugh, Joseph P O’Shea, Anastasios V. Tzingounis, Daniel Schwartz

The paper investigates the impact of the OCNDS-associated CK2K198R mutation on kinase specificity, finding it shifts substrate preferences rather than causing loss of function.

Frontiers in Molecular Biosciences · Apr 19, 2022Peer-reviewedNeuroscience

Reprogramming protein kinase substrate specificity through synthetic mutations

Joshua M. Lubner, George M. Church, Michael F. Chou, Daniel Schwartz

This study reprograms DYRK1A kinase specificity through synthetic mutations to mimic CK II substrate preferences, establishing a high-resolution specificity model.

bioRxiv · Dec 5, 2016 · PreprintBiochemistry