Integrated whole-genome and transcriptome sequencing reveals divergent evolutionary processes across biliary tract cancer subtypes
Felix E.G. Beaudry, Duhan Yendi, Danielle Arshinoff, Nicholas D Light, Simona Perrotti, Erin Winter, Liam R. Cristant, Jingxiong Xu, Julie M. Wilson, Anna Dodd, Roxana Bucur, Eric Xueyu Chen, Elena C. Elimova, Rebecca K.S. Wong, Aruz Mesci, , Robert C. Grant
The paper uses whole-genome and transcriptome sequencing to identify two consensus cancer subtypes in biliary tract cancer, revealing divergent molecular landscapes that better explain tumor heterogeneity than anatomical classification.
bioRxiv · Aug 26, 2026 · PreprintCancer Biology