Molecular basis of stepwise cyclic tetra-adenylate cleavage by the type III CRISPR ring nuclease Crn1/Sso2081
Liyang Du, Danping Zhang, Zhipu Luo, Zhonghui Lin
This study determines the crystal structures of Crn1/Sso2081 in different states to elucidate the mechanism of cA4 cleavage by the type III CRISPR ring nuclease.
Nucleic Acids Research · Feb 4, 2023Peer-reviewedMolecular Biology