Pioneer factor ETV2 safeguards endothelial cell specification by recruiting the repressor REST to restrict alternative lineage commitment
Danyang Chen, Xiaonuo Fan, Ninghe Sun, Kai Wang, Liyan Gong, Juan M. Melero‐Martin, William T. Pu
This study identifies ETV2's role in endothelial cell specification by recruiting REST to repress alternative lineage genes through single-cell RNA-seq and ATAC-seq analyses.
Nature Cardiovascular Research · Jun 10, 2025Peer-reviewedCell Biology