Targeting NAT10 Activates Tumor-Intrinsic Immunity and Suppresses Tumor Progression in Head and Neck Squamous Cell Carcinoma
Thurbu Tshering Lepcha, Nithya Paruchuri, Dawei Zhou, Guillaume N. Fiches, Jinshan He, K.A.S.N. Shanaka, Liu Y, Suha Eleya, Nischal Koirala, J F Zhu, Darrion Mitchell, W Zhao, Netty G. Santoso
This study identifies NAT10 as a suppressor of tumor-intrinsic immunity in HNSCC, showing that its inhibition enhances immune responses and suppresses tumor progression.
bioRxiv · Aug 8, 2026 · PreprintCancer Biology