Author

David J Edwards

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Assay:whole-genome sequencing· 3 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kathryn E Holt· 3 shared Jane Hawkey· 2 shared Claire Gorrie· 1 shared Edward C Holmes· 1 shared François-Xavier Weill· 1 shared Heiman FL Wertheim· 1 shared Helen Billman-Jacobe· 1 shared Kelly L Wyres· 1 shared

Activity by Year

2014-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersEvolutionary Biology

Kathryn E Holt

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3 papers

Recent·Most cited

Genome-scale rates of evolutionary change in bacteria

Sebastian Duchêne, Kathryn E Holt, François-Xavier Weill, Simon Le Hello, Jane Hawkey, David J Edwards, Mathieu Fourment, Edward C Holmes

The paper estimates genome-scale evolutionary rates in bacteria and finds that rates vary widely, largely due to sampling time, with a strong negative association between time and rate.

bioRxiv · Aug 15, 2016Evolutionary Biology

ISMapper: Identifying insertion sequences in bacterial genomes from short read sequence data

Jane Hawkey, Mohammad Hamidian, Ryan R Wick, David J Edwards, Helen Billman-Jacobe, Ruth M Hall, Kathryn E Holt

ISMapper identifies IS insertion sites in bacterial genomes from short read data with high accuracy across multiple species and conditions.

bioRxiv · Mar 10, 2015Bioinformatics

Extensive capsule locus variation and large-scale genomic recombination within the Klebsiella pneumoniae clonal complex 258/11.

Kelly L Wyres, Claire Gorrie, David J Edwards, Heiman FL Wertheim, Li Yang Hsu, Nguyen Van Kinh, Ruth Zadoks, Stephen Baker, Kathryn E Holt

This study identifies extensive capsule locus variation and large-scale genomic recombination in K. pneumoniae CC258/11, expanding the complex to include ST395 and revealing 11 distinct cps loci.

bioRxiv · Oct 27, 2014Genomics