Recognizing the Continuous Nature of Expression Heterogeneity and Clinical Outcomes in Clear Cell Renal Cell Carcinoma
Xiaona Wei, Yukti Choudhury, Weng Khong Lim, John Anema, Richard Kahnoski, Brian Lane, John Ludlow, Masayuki Takahashi, Hiro-omi Kanayama, Arie Belldegrun, Hyung Kim, Craig Rogers, David Nicol, Bin Tean Teh, Min-Han Tan
The paper develops a continuous gene expression score (CLEAR) for clear cell renal cell carcinoma that outperforms discrete subtypes in prognostic accuracy and treatment outcome correlation.
Scientific Reports · Aug 4, 2017Peer-reviewedCancer Biology