Transcriptome and interactome analyses identify the TP53 interacting gene RCCD1 as a candidate susceptibility gene at the 15p26.1 breast and ovarian cancer risk locus
Jasmine Plummer, Felipe Segato Dezem, Stephanie S. Chen, Subash Dhungana, Deepika Wali, Brian D Davis, Justyna E. Kanska, Niko Safi, Ji-Heui Seo, Rosario I. Corona, Joellen M. Schildkraut, Paul D.P. Pharoah, Kate Lawrenson, Simon Knott, Matthew L. Freedman, , Simon A. Gayther
The paper identifies RCCD1 as a susceptibility gene for breast and ovarian cancer by fine-mapping a risk locus and showing its expression and interaction patterns are associated with cancer risk.
bioRxiv · Sep 29, 2020 · PreprintGenetics