Author

Deepthi Kappala

North Carolina State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Amit SharmaiD· 2 shared Anuja Pimplapure· 2 shared Alexis Sauer· 1 shared Amol S. SuryawanshiiD· 1 shared Anna Smith· 1 shared Emma Atwood· 1 shared Haidyn Weight· 1 shared Jacob S. YountiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Amit SharmaORCID

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2 papers

Recent·Most cited

HIV-1 envelope glycan loss links receptor adaptation and innate immune escape in SHIVs

Anna Smith, Haidyn Weight, Revansiddha Katte, Deepthi Kappala, Anuja Pimplapure, Vidya Mangala Prasad, Maolin Lu, Julie Overbaugh, Amit Sharma

This study shows that HIV-1 envelope glycan loss in SHIVs improves CD4 receptor utilization and reduces IFN restriction, linking receptor adaptation and immune escape.

bioRxiv · Oct 13, 2026 · PreprintMicrobiology

Gene duplication and retrotransposition diversify the antiviral repertoire of macaque IFITM proteins

Deepthi Kappala, Alexis Sauer, Emma Atwood, Yuexiu Zhang, Anuja Pimplapure, Naveen Bektas-Jolly, Lohitha Gujjari, Kasturi Chandra, Yogesh Saini, Jacob S. Yount, Amol S. Suryawanshi, Jiànróng Lǐ, Amit Sharma

This study characterizes the antiviral activities and regulatory mechanisms of diverse IFITM proteins in macaques, showing how gene duplication and retrotransposition generate functional diversity in antiviral defenses.

bioRxiv · Jun 11, 2026 · PreprintMicrobiology