Proteomic Analysis of Human Chronic Traumatic Encephalopathy Brain Implicates Proteasome and Ribosome Dysfunction in Disease Progression
Helen E. Pennington, Dillon Shapiro, Jenny A Empawi, Nurgül Aytan, Victor E. Alvarez, Jesse B Mez, Michael Louis Alosco, Xiaoling Zhang, Ann Carolyn McKee, Thor D. Stein, Jonathan D. Cherry, Adam Thomas Labadorf
This study identifies proteomic changes in CTE brains, linking proteasome and ribosome dysfunction to disease progression and clinical features.
bioRxiv · Feb 14, 2026 · PreprintMolecular Biology