Single-Cell Profiling Reveals Developmental Trajectories and identifies SYK and TIM3 as Targets in some T Cell Lymphomas
Ruoyan Li, Jamie D. Matthews, Emily R. James, Carla Vazquez Amos, Olli Dufva, Shuang Li, Christopher J. Steel, Lorenz Kretschmer, Chenqu Suo, Philip Turton, Ruth F. Jarrett, Ekaterina M. Shelomentseva, Egor Volchkov, Dmitry Abramov, Maria‐Myrsini Tzioni, , Suzanne Dawn Turner
This study uses single-cell transcriptomics to analyze T cell lymphomas, identifies developmental origins, and discovers SYK and TIM3 as potential therapeutic targets.
bioRxiv · Mar 30, 2026 · PreprintCancer Biology