Author

Donghui Cheng

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Owen N. WitteiD· 3 shared Beatrice D. ZhangiD· 2 shared Harry Taegyun YangiD· 2 shared Jami McLaughlin· 2 shared John W. Phillips· 2 shared Yi XingiD· 2 shared Alex LeeiD· 1 shared Ameya S. ChamphekariD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioengineering

Owen N. WitteORCID

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Author profile →

3 papers

Recent·Most cited

Systematic mapping of emergent transcriptional states in interacting single-cell dyads by Cell-Cell-seq

Sevana Baghdasarian, Qingyang Wang, Justin Langerman, Zhiyuan Mao, Heather Wright, Caitlin Gee, Donghui Cheng, Jami McLaughlin, Lee Jc, Xiaojing Tina Chen, K. Christopher García, Jingyi Jessica Li, Owen N. Witte, Kathrin Plath, Dino Di Carlo

Cell-Cell-seq maps transcriptional states in interacting cell pairs by profiling defined dyads, revealing emergent gene programs and cross-cell coordination in tumor-T cell interactions.

bioRxiv · Feb 9, 2026 · PreprintBioengineering

The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells

Xinyuan Chen, Harry Taegyun Yang, Beatrice D. Zhang, John W. Phillips, Donghui Cheng, Frank Rigo, Owen N. Witte, Yi Xing, Douglas L. Black

The paper identifies hnRNP H and F as regulators of Myc-dependent HRAS exon splicing in prostate cancer, showing their roles in splicing activation and correlation with Myc hallmarks.

Proceedings of the National Academy of Sciences · Jul 3, 2023Peer-reviewedMolecular Biology

IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing

Yang Pan, John W. Phillips, Beatrice D. Zhang, Miyako Noguchi, Eric Kutschera, Jami McLaughlin, Pavlo A. Nesterenko, Zhiyuan Mao, Nathanael Joshua Bangayan, Robert Wang, Wendy Tran, Harry Taegyun Yang, Yuanyuan Wang, Yang Xu, Matthew B. Obusan, , Yi Xing

IRIS identifies cancer immunotherapy targets from alternative splicing using transcriptomics data and validates them with patient T cells.

Proceedings of the National Academy of Sciences · May 16, 2023Peer-reviewedBioinformatics