GlRac Regulates an ATG8-Independent Autophagy-Like Pathway in Giardia lamblia
Angélica Hollunder Klippel, Corryn Newman-Boulle, Grant Reed, Dule Dule, Saanya Kedia, Martin T. Kelty, Wai Pang Chan, Han-Wei Shih, Alexander R. Paredez
This study identifies an ATG8-independent autophagy-like pathway in Giardia lamblia regulated by GlRac, showing structural and functional similarities to canonical autophagy despite lacking most ATG genes.
PLoS Pathogens · Oct 6, 2026Peer-reviewedCell Biology