BioengineeringbioRxivPreprint
Amyloid-β-regulated gene circuits for programmable Alzheimer's disease therapy
Madeline R. Spetz, Hyosung Kim, Alexander P Ligocki…·Jonathan M. Brunger
This paper develops A{beta}-sensitive synthetic Notch receptors for engineered astrocytes to target amyloid-{beta} in Alzheimer's disease and modulate the neurodegenerative niche.
3 citations