Template-Directed RIG-I Agonist Assembly for Targeted Cancer Immunotherapy
S. K. Ghosh, N. Robertson, E. Crosier, M. Dudley, Q. P. Liu, Z. Medarova
This paper develops a tumor-selective RIG-I agonist that induces type-I IFN signaling and tumor cell apoptosis through template-directed assembly using miRNA-21.
bioRxiv · Dec 8, 2022 · PreprintBioengineering