Spontaneous selection of Cryptosporidium drug resistance in a calf model of infection
M. M. Hasan, E. E. Stebbins, R. K. M. Choy, J. R. Gillespie, E. de Hostos, P. J. Miller, A. Mushtaq, R. M. Ranade, J. E. Teixeira, C. L. M. J. Verlinde, A. Sateriale, Z. Zhang, D. M. Osbourn, D. W. Griggs, E. Fan, , C. D. Huston
This study reports the spontaneous emergence of drug resistance in Cryptosporidium parvum infected calves treated with a methionyl-tRNA synthetase inhibitor, highlighting the potential for anticryptosporidial resistance.
bioRxiv · Jan 4, 2021Microbiology