Tumour architecture inverts ARNT-dependent growth regulation and reveals CPE-mediated spheroid expansion in luminal breast cancer
Hande Özkan, Ferzan Betul BERBER, Elif Kansız, Ezgi Nur CATI, Mustafa Sami Özaydın, Zehra Canbulat, E. Guzar, Begum DURDAR, Dilek Telci, Gözde Korkmaz
This study shows that ARNT's role in breast cancer growth changes with tumor architecture, with CPE mediating spheroid expansion in luminal breast cancer.
bioRxiv · Oct 29, 2026 · PreprintCancer Biology