In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe
M. R. Volpe, M. R. Wilson, C. A. Brotherton, E. S. Winter, S. E. Johnson, E. P. Balskus
This study characterizes the in vitro activity of ClbP, a peptidase involved in colibactin biosynthesis, and develops a fluorogenic probe to detect its activity.
bioRxiv · Feb 24, 2019Biochemistry