Insights from Comparison of the Renal and Skin Single Cell Transcriptomes in Lupus Nephritis
E. Der, H. Suryawanshi, P. Morozov, M. Kustagi, B. Goilav, S. Ranabathou, P. Izmirly, R. Clancy, H. M. Belmont, M. Koenigsberg, M. Mokrzycki, H. Rominieki, J. Graham, J. Rocca, N. Bornkamp, , C. Putterman
This study uses scRNA-seq to analyze renal and skin biopsies from lupus nephritis patients, identifying IFN signatures and fibrotic pathways associated with disease heterogeneity and non-response.
bioRxiv · Dec 31, 2019 · PreprintImmunology