The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing
E. Seidel, L. Dassa, E. Oiknine-Djian, D. Wolf, V. T. Khanh Le-Trilling, O. Mandelboim
This paper identifies UL147A as an HCMV protein that specifically downregulates MICA*008 to evade NK cell-mediated killing.
bioRxiv · Jul 17, 2020Immunology