Evidence of Epistatic Interactive Effects of HK1 and GCK Genes on Circulating Hemoglobin A1c Levels
Lihua Wang, Joseph H Lee, Bharat Thyagarajan, Anatoliy I. Yashin, E. Warwick Daw, Thomas T. Perls, Kaare Christensen, Joseph M. Zmuda, Michael A. Province, Ping An
The paper identifies epistatic interactions between HK1 and GCK genes affecting HbA1c levels using Bayesian methods and confirms findings in independent studies.
medRxiv · May 3, 2026 · PreprintGenetic & Genomic Medicine