NeurosciencebioRxivPreprint
Pathological tau leads to network hyperexcitability through neuronal-subtype-specific functional impairment
Changyi Ji, Yunlu Zhu, Hediye Erdjument‐Bromage…·Einar Sigurdsson
This study shows that the MAPT P301L mutation causes neuronal network hyperexcitability through subtype-specific tau pathology and altered synaptic transmission.
DOI 10.64898/2026.10.05.756807