Lineage tracing of human embryonic development and foetal haematopoiesis through somatic mutations
Michael Spencer Chapman, Anna Maria Ranzoni, Brynelle Myers, Nick Williams, Tim H. H. Coorens, Emily Mitchell, Timothy M. Butler, Kevin J. Dawson, Yvette E. Hooks, Luiza Moore, Jyoti Nangalia, Philip S. Robinson, Elizabeth Hook, Peter J. Campbell, Ana Cvejic
This study uses whole-genome sequencing of single-cell haematopoietic colonies to trace lineage and divergence of embryonic and extra-embryonic tissues in human fetal development.
bioRxiv · May 29, 2020 · PreprintGenomics