Author

Ellen G. F. Borg

Genmab (Netherlands)

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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Aran F. LabrijniD· 1 shared Frank J M BeurskensiD· 1 shared Johannes PreineriD· 1 shared Jürgen StrasseriD· 1 shared Nikolaus Frischauf· 1 shared

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Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedOct 22, 2024

Complement activation by IgG subclasses is governed by their ability to oligomerize upon antigen binding

Nikolaus Frischauf, Jürgen Strasser, Ellen G. F. Borg…·Johannes Preiner

This study shows that IgG subclass complement activation depends on their ability to form oligomers on antigen surfaces, challenging the traditional view of C1 affinity.

44 citationstop 2%

experimental assayhost-pathogen & immune response