BRCA1 is a molecular correlate of cell proliferation in human brain development and in Group 3 and 4 medulloblastoma
Ian Cheong, Xinghan Sun, Leo H.K. Lau, Nishka Kishore, Andrea Senff‐Ribeiro, Ander Díaz‐Navarro, Hana Hajari, Ellen Mak, Rhea Ahluwalia, Luca Bianchini, Jagir Singh Sandhu, Michael D. Taylor, Lena M. Kutscher, Lincoln David Stein, Shraddha Pai
The paper shows BRCA1 correlates with proliferation in human neural progenitor cells and medulloblastoma, particularly in Group 3 and 4 tumors, and is linked to worse prognosis.
bioRxiv · Apr 3, 2025 · PreprintGenomics