Replication Fork-Associated Checkpoint Mediator Mrc1/Claspin Acts in Arrest-Independent Double-Strand Break Survival
Marissa Ashton, Elliot Busch, James E. Haber
The paper identifies Mrc1/Claspin as a novel regulator of DSB repair independent of the Mec1 checkpoint, showing it promotes DSB survival through end-tethering and limiting resection.
bioRxiv · Sep 17, 2026 · PreprintMolecular Biology