Author

Elliot Layne

Mila - Quebec Artificial Intelligence InstitutePrimary ORCID profile (0009-0008-7328-5189 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Elliot LayneiD2 papers · ProteinQure (Canada)

Biology Disciplines

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Research Focus:eQTL / molecular QTL mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:polygenic risk· 1 Approach:statistical model· 1

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Mathieu BlanchetteiD· 1 shared Shadi ZabadiD· 1 shared Yue LiiD· 1 shared

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2024-2024 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Mathieu BlanchetteORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 14, 2024

Multi-ancestry polygenic risk scores using phylogenetic regularization

Elliot Layne, Shadi Zabad, Yue Li, Mathieu Blanchette

This paper introduces DendroPRS, a machine learning method that improves genotype-to-phenotype prediction across diverse ancestries by incorporating phylogenetic relationships.

DOI 10.1101/2024.02.14.580313

humanGWAS summary statistics