Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their excreted vesicles
Larise Oberholster, Amandine Mathias, Sylvain Perriot, Emma Blaser, Mathieu Canales, Samuel Jones, Lucas Culebras, Marie Gimenez, G. Campbell Kaynor, Alexey Sapozhnik, Kevin Richetin, Susan E. Goelz, Renaud Du Pasquier
This study shows JCPyV infects astrocytes, dysregulates cell biology, and affects excreted vesicles, providing insights into PML pathogenesis.
bioRxiv · Apr 11, 2023 · PreprintNeuroscience