Morphological map of under- and over-expression of genes in human cells
Srinivas Niranj Chandrasekaran, Eric Alix, John Arévalo, Adriana Borowa, Patrick J. Byrne, William G Charles, Zitong Chen, Beth A. Cimini, Boxiong Deng, John G. Doench, Jessica Ewald, Briana Fritchman, Colin J. Fuller, Jedidiah Gaetz, Amy B. Goodale, , Anne Elizabeth Carpenter
The paper presents a comprehensive genetic perturbation dataset using Cell Painting to analyze gene expression effects in human cells, revealing novel gene clusters and functional relationships.
Nature Methods · Aug 1, 2025Peer-reviewedBioinformatics