Single-Cell Multiomic Profiling Uncovers Radiation Dosage-Sensitive, Cluster-Specific Regulatory Dynamics in Glioblastoma
Khoi Huynh, Sara Nalina Barcik Weissman, Cheol H. Park, Maria L. G. Quiloan, Blake Sun Chang, Eric Chang, Kelly Street, David Dinh Tran, Aram Sandaldjian Modrek
This study uses single-cell multiomic profiling to show radiation-induced transcriptional and chromatin remodeling in GBM, revealing dose-dependent and cluster-specific regulatory changes.
bioRxiv · Dec 3, 2025 · PreprintCancer Biology