Metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia can be targeted using Venetoclax
Dallas Jones, Elena Woods, Zhenhua Li, Kristin L. Schaller, Eric Hoffmeyer, Ben Kooiman, Joseph Fernandez, Tegan Wharton, Dejene Tufa, Spencer C. Hall, George Trahan, Kelly W. Maloney, Holly Pacenta, Kelly Sullivan, Joaquin Espinosa, , Michael R. Verneris
This study identifies metabolic vulnerabilities in Down syndrome B-cell acute lymphoblastic leukemia and shows that Venetoclax effectively targets these vulnerabilities.
Haematologica · Oct 22, 2026Peer-reviewedCancer Biology