et al

A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia

The paper identifies a 5-transcript signature in blood samples that distinguishes bacterial from viral pneumonia with high accuracy.

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder

This study identifies 30 genome-wide significant loci for obsessive-compulsive disorder (OCD) using a large GWAS, linking risk to specific brain cell types and shared genetic risk with other psychiatric and non-psychiatric traits.

Cystatin C is glucocorticoid-responsive, directs recruitment of Trem2+ macrophages and predicts failure of cancer immunotherapy

This study identifies Cystatin C as a glucocorticoid-responsive factor that recruits Trem2+ macrophages and predicts immunotherapy failure in cancer.

Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people

This paper conducts genome-wide association studies on reading- and language-related skills in 34,000 people, identifying genetic variants and shared genetic factors across multiple traits.

Heterozygous variants in KMT2E cause a spectrum of neurodevelopmental disorders and epilepsy

This paper reports on 38 individuals with KMT2E variants, finding that heterozygous variants cause neurodevelopmental disorders, epilepsy, and variable expressivity by sex.

10Kin1day: A bottom-up neuroimaging initiative

The paper describes a collaborative neuroimaging initiative that brought together researchers to analyze 10,000+ MRI connectivity datasets and released 8,000+ MRI connectome maps.

Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

The paper analyzes cerebral cortical asymmetry in 17,141 healthy individuals, finding widespread hemispheric and regional asymmetries, associations with sex, age, brain size, and heritability.