Generalisable tissue-wide molecular reconstruction from histology
Andrew Zhang, Lijia Yu, Beilei Bian, Yue Cao, Shuchang Ye, Ethan Han, Harry Robertson, Yan Dong, Yixiao Mao, Boxiang Liu, Ellis Patrick, Jinman Kim, Jean Yee Hwa Yang
GHIST+ reconstructs tissue-wide molecular maps from H&E histology, enabling cohort-scale molecular reconstruction from sparse spatial transcriptomic data.
bioRxiv · Jun 12, 2026 · PreprintBioinformatics