Deep Learning-Guided Holotomography Reveals Early Structural Remodelling During Pluripotency Exit
Hoewon Park, Geon Kim, Jeongwon Shin, Seohyun Kim, Eui-been Hwang, M U Kim, Taewoong Hwang, 임아림, Gyungtae Yoon, J Park, Young-woo Jeon, Nam-Shik Kim, YongKeun Park, Ki‐Jun Yoon
DeepHOPE uses deep learning and 3D imaging to assess pluripotency in hPSCs, detecting structural changes before molecular loss of pluripotency.
bioRxiv · Apr 27, 2026 · PreprintDevelopmental Biology